Prof. Plum is last to roll in the board game.

Professor Plum is a psychiatrist in the movie. Mr. Boddy knows Plum's secret, that he had an affair with one of his patients, and blackmails him for it.

In Clue: The Movie, Prof. Plum is played by Christopher Lloyd.

Prof. Plum is a panicky scientist. He invents a poison which he used to kill his wife (Mr. Boddy's daughter) via a freak accident, and which everyone steals to try to kill everyone else with during the course of the VCR Game.

Plum accompanies Green in blackmailing the other guests with Mrs. White's diary. However, the plan backfires when their secrets are also revealed.

In the VCR Mystery Game, Professor Plum is played by Jack Neary.

Professor Plum is a college gym teacher in the puzzle set.

Professor Plum plays his usual brainy self in the SNES Video Game.

Another unique character, Plum plays the absent-minded professor who would forget his head if it wasn't screwed on. In one chapter, he invents a cloning device which he accidentally uses to clone Mrs. Peacock. After he does this, Plum forgets how to make the cloning machine reverse it. During that time, the guests grow to detest Plum — until White discovers how to tell the true Mrs. Peacock from the clones.

Peter Plum is essentially a boring little boy who's as obsessed with Clue Jr as all the other children.

Bart Simpson plays Professor Plum.